Active B-Vitamin Complex Formula
This comprehensive B-vitamin supplement combines three essential nutrients in their most bioavailable forms. Each capsule delivers 5000mcg methylcobalamin B12, 400mcg L-methylfolate (active B9), and 10mg pyridoxal 5′-phosphate (P5P) B6.
The formula uses active forms that your body recognises immediately without requiring conversion steps. This approach ensures optimal absorption and cellular availability.
Why Active Forms Matter
Standard supplements use cyanocobalamin B12, synthetic folic acid, and pyridoxine B6. Your body must convert these forms through enzymatic processes before cells use them.
Active forms bypass conversion entirely. Methylcobalamin B12, L-methylfolate, and P5P enter your bloodstream ready for immediate cellular uptake. This direct bioavailability benefits everyone, particularly those with genetic variations affecting B-vitamin metabolism.
Vitamin B12 (Methylcobalamin) – 5000mcg
Methylcobalamin is the coenzyme form of vitamin B12 found naturally in your body. This form participates directly in methylation reactions and nervous system maintenance.
Key Functions:
- Supports red blood cell formation and prevents megaloblastic anaemia
- Maintains myelin sheath integrity around nerve fibres
- Participates in DNA synthesis and cell division
- Contributes to homocysteine metabolism
- Supports energy-yielding metabolism by converting food into cellular energy
- Maintains normal psychological function
The 5000mcg dose provides substantial support for those with increased B12 requirements, including vegetarians, vegans, older adults, and individuals with absorption challenges.
L-Methylfolate (Active Folate) – 400mcg
L-methylfolate (5-MTHF) is the biologically active form of vitamin B9. Your cells use this form directly for essential metabolic processes.
Key Functions:
- Supports maternal tissue growth during pregnancy
- Maintains normal homocysteine levels
- Contributes to blood formation
- Supports cell division processes
- Reduces tiredness and fatigue
- Maintains psychological function
- Supports immune system function
The 400mcg dose meets daily folate requirements without the concerns associated with unmetabolised synthetic folic acid. L-methylfolate works effectively regardless of MTHFR genetic variations.
Pyridoxal 5′-Phosphate (P5P) – 10mg
P5P is the active coenzyme form of vitamin B6. This form functions immediately in over 100 enzymatic reactions throughout your body.
Key Functions:
- Supports protein and glycogen metabolism
- Contributes to red blood cell formation
- Maintains normal nervous system function
- Supports immune system health
- Regulates hormonal activity
- Reduces tiredness and fatigue
- Supports normal cysteine synthesis
- Maintains psychological function
The 10mg dose provides substantial support for B6-dependent metabolic pathways.
Synergistic B-Vitamin Action
These three B vitamins work together in interconnected metabolic pathways. Their combined action produces effects beyond what individual vitamins achieve alone.
Methylation Support B12 and folate work together in the methylation cycle, converting homocysteine to methionine. This process affects DNA synthesis, neurotransmitter production, and cellular detoxification. B6 supports related pathways through separate mechanisms.
Nervous System Function All three vitamins maintain nervous system health through distinct but complementary mechanisms. B12 protects nerve fibres, folate supports neurotransmitter synthesis, and B6 participates in neurotransmitter metabolism.
Blood Cell Formation B12 and folate are essential for red blood cell maturation in bone marrow. B6 supports haemoglobin synthesis. Together, they ensure healthy blood cell production and oxygen transport.
Energy Metabolism Each vitamin contributes to converting dietary nutrients into cellular energy. Their combined action supports efficient energy production from proteins, carbohydrates, and fats.
Who Benefits From This Formula
Plant-Based Diets Vegetarians and vegans require B12 supplementation as this vitamin occurs naturally only in animal products. The methylcobalamin form ensures optimal absorption without dietary B12 sources.
Pregnancy Planning and Pregnancy Women trying to conceive or who are pregnant need increased folate for foetal development. The 400mcg methylfolate dose supports maternal tissue growth and reduces neural tube defect risk.
Genetic Variations Individuals with MTHFR or other genetic variations affecting B-vitamin metabolism benefit from pre-activated forms that bypass conversion requirements.
Age-Related Changes Adults over 50 often experience reduced stomach acid production, which decreases B12 absorption from food. The high-dose methylcobalamin compensates for reduced absorption efficiency.
Increased Requirements Certain medications, health conditions, and lifestyle factors increase B-vitamin needs. This formula provides substantial doses to meet elevated requirements.
Quality Manufacturing Standards
Royal Oak Health manufactures this supplement in BRC Grade AA certified UK facilities. The company holds GMP (Good Manufacturing Practice) certification, ensuring consistent quality and safety standards.
Each batch undergoes testing to verify ingredient identity, purity, and potency. The formula contains exactly what the label states, with no hidden ingredients or contaminants.
The company has produced supplements since 1999, establishing a track record of reliable, tested products. Royal Oak Health received the British Made Awards recognition for Best Food Supplements Manufacturer.
Clean Formula Composition
The vegetarian capsules use hydroxypropyl methylcellulose (HPMC) shells. This plant-derived material contains no animal products or gelatin.
Rice flour (Oryza sativa) serves as the only additional ingredient, providing structure within the capsule. The formula contains no unnecessary fillers, binders, or flow agents.
Free from common allergens: no gluten, lactose, soya, nuts, or dairy. Contains no GMO ingredients. Suitable for vegetarian and vegan diets.
Dosage and Usage
Take one capsule daily with water, preferably with food. Food intake supports absorption and reduces potential stomach sensitivity.
Each bottle contains 60 capsules, providing a 2-month supply at the recommended daily dose. Consistent daily supplementation maintains steady B-vitamin levels in your system.
Do not exceed the stated dose unless directed by a healthcare professional. Store in a cool, dry place away from direct sunlight.
Safety Considerations
This product is a food supplement and does not replace a varied, balanced diet and healthy lifestyle. Consult your healthcare provider before use if you are pregnant, breastfeeding, taking medications, or have medical conditions.
B vitamins are water-soluble, meaning your body excretes excess amounts through urine. The high B12 dose is considered safe as your body regulates absorption and eliminates surplus amounts.
If you experience any adverse reactions, discontinue use and consult your healthcare provider. Keep out of reach of children.
Key benefits list
- Triple Active Formula Three essential B vitamins in their most bioavailable forms. Methylcobalamin B12, L-methylfolate B9, and P5P B6 work without conversion steps.
- High-Strength B12 5000mcg methylcobalamin per capsule provides substantial support. Addresses increased requirements and absorption challenges.
- Active Methylfolate 400mcg L-methylfolate bypasses MTHFR genetic variations. Works immediately without conversion requirements.
- P5P Coenzyme Form 10mg pyridoxal 5′-phosphate supports over 100 enzymatic reactions. Active B6 form functions directly in metabolism.
- Energy Metabolism Support All three vitamins contribute to converting food into cellular energy. Reduces tiredness and fatigue through multiple pathways.
- Nervous System Maintenance Combined support for nerve function, neurotransmitter synthesis, and myelin protection. Maintains psychological function.
- Blood Formation Essential nutrients for red blood cell production and maturation. Supports healthy oxygen transport throughout the body.
- Methylation Pathway Support B12 and folate work together in methylation cycles. Maintains healthy homocysteine metabolism and DNA synthesis.
- Plant-Based Friendly Vegan capsules with no animal-derived ingredients. Essential B12 supplementation for vegetarian and vegan diets.
- UK Manufacturing Quality GMP certified, BRC Grade AA facilities. Batch tested for purity and potency. Award-winning manufacturer since 1999.
- Clean Label Formula No unnecessary fillers or additives. Free from gluten, lactose, soya, and GMO ingredients. Rice flour as the only excipient.
- 2-Month Supply 60 capsules provide extended supplementation. One capsule daily covers two months of nutritional support.
Frequently Asked Questions
Active forms (methylcobalamin, L-methylfolate, P5P) bypass enzymatic conversion steps required for standard forms (cyanocobalamin, folic acid, pyridoxine). Your cells use active forms immediately upon absorption. This approach benefits everyone, especially those with genetic variations like MTHFR that reduce conversion efficiency. Active forms ensure consistent bioavailability regardless of individual metabolic differences.
Yes, this dose is considered safe. Vitamin B12 is water-soluble, meaning your body excretes excess amounts through urine rather than storing them. Your intestinal absorption of B12 is self-regulating—as intake increases, absorption percentage decreases. High doses compensate for reduced absorption efficiency, particularly beneficial for older adults, those with digestive conditions, or people taking certain medications. Consult your healthcare provider about individual needs.
This formula benefits vegetarians and vegans lacking dietary B12 sources, women planning pregnancy or who are pregnant needing folate support, individuals with MTHFR or similar genetic variations, adults over 50 with reduced nutrient absorption, and anyone with increased B-vitamin requirements due to medications, health conditions, or lifestyle factors. The high-strength active forms address various supplementation needs effectively.
Take one capsule daily with food, preferably at the same time each day. Food enhances absorption and reduces potential stomach sensitivity. Morning or evening dosing works equally well—choose the time that fits your routine. Consistency matters more than specific timing. B vitamins support energy metabolism, so some people prefer morning intake, though the effect is subtle.
B vitamins interact with several medications. Metformin (diabetes medication) reduces B12 absorption. Proton pump inhibitors and H2 blockers (acid reflux medications) decrease B12 absorption from food but not from supplements. Some anticonvulsants interact with folate. Levodopa (Parkinson’s medication) interacts with vitamin B6. Always inform your healthcare provider about all supplements when discussing medications or starting new prescriptions.
