CLA 3000mg 180 Softgels 80% Active Isomers

What CLA Research Actually Shows — A Genuinely Mixed Picture

This product provides 3000mg of active CLA per 3-softgel serving, from 3750mg of safflower oil standardised to 80% Conjugated Linoleic Acid content.

This product’s label doesn’t specify the ratio of CLA isomers — commercial Conjugated Linoleic Acid supplements typically use a roughly 50/50 blend of two isomers (cis-9, trans-11 and trans-10, cis-12) unless otherwise stated, and it’s reasonable to assume this is the case here in the absence of further detail. This matters because the two isomers behave differently in research: some randomised trials, including one 12-week study in overweight and obese women, found meaningful reductions in body fat with Conjugated Linoleic Acid supplementation and no adverse effects on liver function.

However, a broader review of 13 controlled human trials found little consistent evidence that CLA reduces body weight overall, and some research has specifically linked the trans-10, cis-12 isomer, at higher doses, to reduced insulin sensitivity and increased liver fat accumulation in animal and some human studies — essentially the opposite of the intended effect.

Given this, if you have diabetes, insulin resistance, or an existing liver condition, it’s worth discussing Conjugated Linoleic Acid supplementation with your GP before starting, rather than assuming it’s automatically beneficial for metabolic health. Reported side effects in research include digestive upset.

Sourced from safflower oil, vegan (tapioca starch and glycerine softgel), gluten-free, lactose-free, non-GMO, manufactured in the EU. Take 3 softgels daily, preferably with a meal, or as directed by your healthcare practitioner. Not suitable for under-18s. Speak to your GP before use if you have diabetes, insulin resistance, a liver condition, are pregnant, breastfeeding, or take regular medication.

The Research Behind This Product