Nattokinase is studied for its effect on blood clotting — which is exactly why it isn’t suitable for everyone, particularly anyone on blood-thinning medication. Before choosing a product, please see our complete guides to Nattokinase for Heart Health and Nattokinase and Arterial Health, which cover the safety considerations in full before anything else. Below you’ll find our picks, measured in fibrinolytic units (FU) for consistent potency.
Nattokinase
Before Choosing a Nattokinase Supplement
Speak to your GP before considering nattokinase if you use blood-thinning medication (warfarin, aspirin, clopidogrel), take high-dose omega-3 or ginkgo biloba, have surgery scheduled, are pregnant or breastfeeding, or have a bleeding disorder. This isn’t a minor caveat — it’s the single most important thing to know before buying. Research studies have generally used 1,000-2,000 FU daily. Our full guides cover what the cardiovascular research actually shows, and the arterial health-specific evidence, in complete detail.