Organic Ashwagandha KSM-66 with 5% Withanolides 60 Capsules

Two Safety Points Worth Adding Before You Start

This capsule provides 500mg of KSM-66 ashwagandha, a root-only extract using a solvent-free “Green Chemistry” extraction process, backed by a genuinely substantial body of 22 human clinical trials — this is accurate, and KSM-66 does have one of the stronger evidence bases among ashwagandha extracts specifically, particularly for cortisol reduction and stress-related outcomes.

It’s worth correcting the “immune support” framing in this product’s title: ashwagandha’s best-supported research area is stress and cortisol regulation specifically, not general immune support — this is a more accurate description of where the strongest evidence actually lies.

A genuinely important safety finding worth sharing: a 2020 case series published in Liver International documented 10 cases of ashwagandha-associated liver injury (5 from Iceland, 5 from the US Drug-Induced Liver Injury Network), with a median onset around 4 weeks after starting, and one patient requiring evaluation for liver transplant. The NIH’s official LiverTox database now rates ashwagandha’s hepatotoxicity potential as “Probable.” This appears rare relative to how widely ashwagandha is used, and a 2021 randomised trial testing 1,000mg daily for 30 days found no significant liver enzyme changes — but the case reports are real. If you notice unusual fatigue, yellowing skin or eyes, dark urine, nausea, or abdominal pain after starting, stop taking it and see your GP promptly, particularly if you have an existing liver condition or drink alcohol regularly.

Separately, ashwagandha can affect thyroid hormone levels — if you have a thyroid condition or take thyroid medication, this needs a GP conversation before starting.

Many integrative practitioners recommend cycling ashwagandha (8-12 weeks on, 4 weeks off) as a precautionary measure, though this is a conservative approach rather than an evidence-based requirement.

Soil Association certified organic, sourced from India, vegan, manufactured in the UK to GMP and BRC standards. Take one capsule daily with food or water. Not suitable for under-18s. Speak to your GP before starting if you have a thyroid condition, an existing liver condition, drink alcohol regularly, are pregnant, breastfeeding, or take prescription medication — and stop use and seek medical attention if you notice any signs of liver-related symptoms.

The Research Behind This Product